

Osteosarcoma is the most common type of bone cancer in dogs, and it’s something that every pet owner should be aware of. This aggressive disease usually develops in the long bones of the legs, but can also manifest in other bones of the body.
It’s a condition that mostly affects large and giant dog breeds, all starting in the osteoblasts. Osteoblasts are cells responsible for building and reshaping bone. Once osteosarcoma takes hold, it destroys healthy bone tissue and can spread to other nearby areas.
Bone cancer in dogs is a life-threatening condition, which means that quick action is needed. In this blog, we’ll discuss everything you need to know about osteosarcoma in dogs and how we can help.
What Causes Osteosarcoma in Dogs?
The exact causes of osteosarcoma in dogs aren’t fully understood, but several factors appear to increase a dog’s risk. This includes their genetics, size, and age.
While osteosarcoma can occur in any breed, it is far more common in large and giant breeds
Rottweilers
Irish Wolfhounds
Labrador Retrievers
Age is also another factor. Middle-aged and older breeds are observed to have higher cases, with ages about 6 to 8 years old. Despite this, the condition can still affect puppies.
Additionally, a dog with injuries and bone fractures that weren't able to heal properly is also at risk. Lastly, environmental influences like radiation, carcinogens, and harmful chemicals can increase the risk.
What Are the Symptoms of Osteosarcoma in Dogs?

The symptoms of osteosarcoma in dogs often consist of mobility issues.
Lameness and Limping. One of the most noticeable signs of canine osteosarcoma is difficulty moving. Your dog may start limping, which can become severe over time. This can be seen as favoring one leg when walking and a reluctance to use the affected leg.
Swelling. Dogs can also have significant swelling in the affected area. This is due to the aggressive nature of the cancer, as it grows and invades nearby tissue. The swelling can feel warm to the touch and is typically found on the front and back legs.
Pain. Because the condition destroys healthy bones, it is a very painful disease. Dogs may whimper and cry out when moving. They will be visibly uncomfortable.
Lethargy and Weakness. In addition to the pain, dogs will be lethargic and weak, preferring to lie down and rest rather than play.
Loss of Appetite and Weight Loss. Dogs will also lose interest in eating, even when given their favorite foods and treats.
Behavioral Changes. Dogs with osteosarcoma will be distraught, irritable, or aggressive because of the pain. They can also become more withdrawn and restless.
Pathological Fractures. The dog’s bones can also break even with minimal stress or trauma. These can be extremely painful.
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