Hypothyroidism in Cats: Causes, Signs and Symptoms, and Treatment

Hypothyroidism in Cats: Causes, Signs and Symptoms, and Treatment

Published Date

Published Date

June 11, 2025

June 11, 2025

Last Updated

Last Updated

September 22, 2025

September 22, 2025

A veterinarian is holding a cat for a checkup while the pet owner helps by keeping it still.
A veterinarian is holding a cat for a checkup while the pet owner helps by keeping it still.
A veterinarian is holding a cat for a checkup while the pet owner helps by keeping it still.

Cats are masters of subtlety. They curl into quiet corners when they’re not feeling well, sleep a little longer, eat a little less or more, and rarely raise alarm bells. But what if those small changes are actually them calling out for help?

Hypothyroidism in cats is rare, but it can still occur. When it does, it affects everything from a cat's energy levels to how their organs function. And if you’re living in a place like the UAE, where heat and dehydration already strain your cat’s system, an underactive thyroid can quietly wreak havoc.

With that, we’re here to explore the facts, the science, and all the signs you shouldn’t ignore. 

What Is Hypothyroidism in Cats?

Feline hypothyroidism is a condition in which the thyroid gland fails to produce enough thyroid hormones, primarily thyroxine (T4). This hormone regulates metabolism, energy, and body temperature. 

In cats, hypothyroidism is far less common than hyperthyroidism, the latter being an overproduction of these hormones.

But make no mistake: just because it’s rare doesn’t mean it’s harmless. The condition is often either congenital (present from birth) or iatrogenic, which means it’s caused by medical treatment, most often for hyperthyroidism.

Feline hypothyroidism is most frequently seen after radioactive iodine therapy, surgical thyroidectomy, or long-term methimazole use. These treatments suppress the thyroid to correct an overactive state, but occasionally, they suppress it too much.

In hot, arid climates like Dubai and Abu Dhabi, where your cat’s metabolism is already adapting to environmental stressors, the symptoms can quietly intensify.

What Triggers Hypothyroidism in Cats?

The two primary causes of feline hypothyroidism are:

Congenital Hypothyroidism

This form is exceptionally rare and typically seen in kittens. It results from abnormal thyroid development or hormone production from birth. These cats often show stunted growth, a dull coat, and a sad kind of lethargy that’s hard to miss once you recognize it.

Iatrogenic Hypothyroidism

By far the more common scenario, this occurs in adult cats as a result of overtreatment for hyperthyroidism. Procedures like thyroid gland removal, radioiodine therapy, or even medication (methimazole) may tip the balance too far, reducing hormone production below healthy levels.

In some cases, the hypothyroidism may resolve on its own. In others, lifelong treatment is necessary.

What Are the Symptoms of Hypothyroidism in Cats?

Signs of Hypothyroidism in Cats

Because hypothyroidism in cats is so uncommon, symptoms often mimic other conditions, or worse, are dismissed as part of “getting older.”

Here are some red flags to watch for:

  • Unexplained weight gain. Cats with hypothyroidism may gain weight even if their diet and activity level have not changed. The slowed-down metabolism makes it harder for cats to burn calories effectively. 

  • Lethargy or lack of interest in play. Along with a slower metabolism, the sluggish thyroid gland can leave cats feeling lethargic, tired, and uninterested in playtime. 

  • Low body temperature. Feline hypothyroidism can also make cats feel colder because it reduces the body’s ability to regulate body heat. 

  • Dry, thinning coat or excessive shedding. A cat with hypothyroidism can also have a much poorer coat quality. This coat will be considerably dry, brittle, and thin. 

  • Constipation. Constipation is also a possible symptom of hypothyroidism in cats. Because they have a slower metabolism, their bowel movements will also be slower. 

  • Mental dullness or "zoned out" behavior. Like their energy levels, they will also appear dull and zoned out. 

  • Slow heart rate (bradycardia). Hypothyroidism in cats can also result in a much slower heart rate, reducing circulation and contributing to weakness. 

  • Sensitivity to cold. Some can feel colder because of their impaired metabolism. You may see cats curling up in blankets and bedding. 

  • Swelling in the neck (goiter). An enlarged thyroid gland can sometimes appear visible around the neck. This happens because the gland is struggling to produce thyroid hormones. 

Need a Thyroid Check for Your Cat?

Need a Thyroid Check for Your Cat?

Book an appointment today at Noble Vet Clinics.

Book an appointment today at Noble Vet Clinics.

How Is Hypothyroidism in Cats Diagnosed?

Two veterinarians in a clinic care for a tabby cat on a metal table. One holds the cat gently while the other takes a blood sample. The setting is calm and professional.

Our vets need to do a thyroid panel, a series of blood tests to diagnose hypothyroidism in cats. 

  • Total T4 Test. A blood sample is collected and analyzed for T4 levels. When this level is low, it indicates hypothyroidism because not enough hormones are being produced. 

  • Free T4 Measurement. Here, the blood sample is analyzed through a free T4 by equilibrium dialysis. This separates unbound thyroxine from protein-bound hormones. Low levels provide a more accurate diagnosis for hypothyroidism. 

  • Thyroid-Stimulating Hormone Test. The blood sample will be analyzed for TSH, which is produced to stimulate the thyroid gland to produce more hormones. If it’s high and T4 levels are low, then the cat has hypothyroidism. 

It’s important to test more than once. Hormone levels can fluctuate, and some cats (especially those post-hyperthyroid treatment) may have transient hypothyroidism.

Treatment for Hypothyroidism in Cats

Most cats will respond well to levothyroxine. It's a synthetic thyroid hormone given once or twice daily. This will be the lifelong medication required for cats to live happy and normal lives. 

The doses will be carefully calibrated depending on the cat's weight and response. Side effects are rare when dosing is correct, but over-supplementation can swing the pendulum back toward hyperthyroidism, so monitoring is crucial.

You’ll need to return for follow-up testing, especially during the first few months. This allows your vet to fine-tune the dosage and ensure stable thyroid hormone levels.

While some iatrogenic cases resolve on their own within a few months (especially after hyperthyroidism treatment), many require lifelong supplementation. And that’s okay. Most cats adjust well, and once stabilized, their energy and personality often return to what you remember.

Is Feline Hypothyroidism Dangerous If Left Untreated?

Yes. When it's left untreated, this can result in impaired organ function, particularly the heart and kidneys. It can also severely stunt the growth and brain development of kittens. Hypothyroidism in cats can also weaken the immune system, slow down metabolism, and reduce the quality of life.

What Can You Do at Home to Support a Hypothyroid Cat?

A veterinarian is smiling and holding a white and orange cat in her arms.

Staying on top of your cat’s treatment will be the best way to support them. 

  1. Give Medication Consistently

Make sure that you stay on top of your cat’s medication. Follow our vet’s prescription and try to give these supplements at the same time each day. 

  1. Visit the Vets

Regular checkups can help us monitor your cat’s condition and adjust anything that needs to be adjusted. 

  1. Monitor Your Cat

Keep an eye out for shifts in your cat’s appetite, energy, and coat quality. If you see any persistent changes that seem to be unexplained, then call our vets. 

  1. Keep Your Cat Hydrated and Cool

Make sure your cat drinks water all the time by providing a fresh supply. Plus, it’s also a big help to keep your cat’s space cool and free from the heat. 

  1. Encourage Gentle Activity

Even if your cat seems sluggish, offer low-key enrichment like interactive cat toys, short play sessions, or puzzle feeders.

How Long Can a Cat Live With Hypothyroidism?

With proper treatment, cats diagnosed with hypothyroidism can live full, happy lives. The condition itself isn’t a death sentence. It’s the complications, untreated weight gain, poor circulation, and organ strain, that can gradually wear down their vitality.

When Should You Visit the Vet for Hypothyroidism Testing?

If your cat seems sluggish, gains weight without dietary changes, or develops a poor coat, don’t wait. It's worth running a thyroid panel. Early detection can prevent months, or even years, of silent suffering.

“Caring for cats means noticing the quiet changes: the ones that don’t shout, but whisper. That’s where early diagnosis begins, and where real healing takes root.”

- Dr. Soheyl Simaei

What’s the Final Word on Hypothyroidism in Cats? Trust the Quiet Clues

Cats rarely ask for help. That’s why it’s up to you to notice what they don’t say. A little extra sleep, a slight weight gain, and a dull look on their coat. These are the whispers of a struggling thyroid.

Frequently Asked Questions

Is hypothyroidism in cats fatal?

Not directly. But if left unmanaged, hypothyroidism can lead to a cascade of other issues: heart problems, lowered immunity, and metabolic stress. Over time, these complications can shorten your cat’s lifespan.

Is hypothyroidism in cats fatal?

Not directly. But if left unmanaged, hypothyroidism can lead to a cascade of other issues: heart problems, lowered immunity, and metabolic stress. Over time, these complications can shorten your cat’s lifespan.

Is hypothyroidism in cats fatal?

Not directly. But if left unmanaged, hypothyroidism can lead to a cascade of other issues: heart problems, lowered immunity, and metabolic stress. Over time, these complications can shorten your cat’s lifespan.

Does breed play a role in hypothyroidism in cats?

Currently, no strong link has been found between breed and feline hypothyroidism. Unlike some other genetic conditions, this one appears to arise more from factors like congenital development or post-treatment shifts after managing hyperthyroidism.

Does breed play a role in hypothyroidism in cats?

Currently, no strong link has been found between breed and feline hypothyroidism. Unlike some other genetic conditions, this one appears to arise more from factors like congenital development or post-treatment shifts after managing hyperthyroidism.

Does breed play a role in hypothyroidism in cats?

Currently, no strong link has been found between breed and feline hypothyroidism. Unlike some other genetic conditions, this one appears to arise more from factors like congenital development or post-treatment shifts after managing hyperthyroidism.

Can diet help cats diagnosed with hypothyroidism?

Diet can support, but not substitute for, treatment. A stable, nutrient-rich, vet-approved diet can reduce metabolic stress and support overall endocrine health. Some cats may benefit from iodine-restricted formulas, especially if they’ve been treated for hyperthyroidism in the past.

Can diet help cats diagnosed with hypothyroidism?

Diet can support, but not substitute for, treatment. A stable, nutrient-rich, vet-approved diet can reduce metabolic stress and support overall endocrine health. Some cats may benefit from iodine-restricted formulas, especially if they’ve been treated for hyperthyroidism in the past.

Can diet help cats diagnosed with hypothyroidism?

Diet can support, but not substitute for, treatment. A stable, nutrient-rich, vet-approved diet can reduce metabolic stress and support overall endocrine health. Some cats may benefit from iodine-restricted formulas, especially if they’ve been treated for hyperthyroidism in the past.

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