Leaky Gut in Dogs: Main Causes, Symptoms, and Treatments

Leaky Gut in Dogs: Main Causes, Symptoms, and Treatments

Published Date

Published Date

September 18, 2025

September 18, 2025

A veterinarian is carefully assessing a dog for leaky gut while another vet is assisting.
A veterinarian is carefully assessing a dog for leaky gut while another vet is assisting.
A veterinarian is carefully assessing a dog for leaky gut while another vet is assisting.

A leaky gut in dogs is a condition in which the lining of the intestines becomes more permeable due to damage. This intestinal permeability is actually dangerous. 

Normally, a dog’s gut acts just like a filter that allows nutrients to get into the bloodstream while keeping toxins, bacteria, pathogens, and other bad things out. A healthy gut microbiome is responsible for maintaining this barrier. 

But when the barrier becomes “leaky,” unwanted substances can slip through and trigger a range of health concerns. 

But before all that, let’s talk more about what leaky gut in dogs is. 

What Is Leaky Gut in Dogs?

At its core, leaky gut in dogs comes from the intestinal lining not doing its job properly. This means that the protective barrier becomes weaker and more permeable, allowing unwanted substances to leak through. The immune system will then recognize these as threats and respond. 

The result is inflammation that can not only damage the digestive tract, but also the skin, joints, and the whole body. In short, leaky gut syndrome in dogs is a problem for the entire system. 

This is often discussed alongside intestinal dysbiosis in dogs. It's because it refers to gut imbalance. When harmful bacteria take over, they can irritate, damage, and weaken the intestinal lining.

What Causes Leaky Gut in Dogs?

This condition generally comes from multiple digestive stressors. 

Poor or Highly Processed Diets

Many commercial dog foods, especially lower-quality kibbles, are packed with fillers, preservatives, and artificial additives. These are often high in wheat, soy, grains, and processed ingredients. Over time, these substances can irritate the digestive tract and contribute to inflammation. 

These foods are not good for supporting a healthy gut microbiome. Plus, some dogs can have sensitivities to these foods that can trigger an immune response and inflammation. 

Medications and Chemicals

While antibiotics, NSAIDs, and medications in general can be life-saving, they also affect good bacteria. This disrupts the gut microbiome and creates a space for harmful bacteria to take over. 

Long-term use of these medications can damage the intestinal lining, making it weaker and increasing the risk of a leaky gut in dogs. 

Along with medications, toxins such as household cleaners, pesticides, and other chemicals can strain the liver and digestive system. When this happens, the lining can also become irritated and inflamed.

Chronic Digestive Disease

Dogs with conditions like inflammatory bowel disease, food intolerances, or pancreatitis are also at risk. It's because these conditions cause repeated episodes of inflammation in the intestines, which can weaken the lining.

Parasites and Infections

Gut parasites such as Giardia or intestinal worms can attach to the intestinal wall and damage it. Along with causing inflammation, these parasites can also disrupt a dog's nutrient absorption. 

Stress and Immune Imbalance

Stress has a huge impact on gut health. When dogs get stressed, cortisol and other stress hormones can disrupt digestion and the gut microbiome. This weakens the microbiome, making the gut lining more vulnerable to irritation. 

What Are the Symptoms of Leaky Gut in Dogs?

Two veterinarians are checking a brown dog's condition to look for signs of leaky gut.

Leaky gut syndrome in dogs can be challenging to pinpoint because its signs are similar to those of many other conditions. 

  • Diarrhea or Constipation. When the gut lining is inflamed, digestion becomes irregular. Some dogs will have loose stools, while others will have difficulty passing them. These are often chronic symptoms. 

  • Gas and Bloating. An imbalance in gut bacteria can cause gas, bloating, and abdominal swelling.

  • Vomiting. Affected dogs may vomit after eating. It’s the body’s way of reacting to the irritation in the intestines. 

  • Abdominal Pain. Dogs with leaky gut syndrome tend to show signs of belly pain. They can whine, have a hunched posture, or be sensitive to touch. 

  • Skin Irritation. Skin problems like itching, redness, or hot spots are common with leaky gut because the inflammation triggers an immune response in the skin. 

  • Ear Infections. Ear infections that just keep coming back are another sign of an imbalanced gut.  

  • Lethargy. Some dogs can feel very tired because their bodies aren't getting nutrients properly. They can appear less playful and prefer to sleep more than before.

  • Joint Pain. Chronic inflammation from leaky gut can spread to the joints, leading to stiffness or discomfort. Some can have difficulty getting up or going on long walks.

  • Behavioral Changes. An imbalanced gut can also affect a dog’s behavior. Some dogs can appear more stressed, while others can become irritable. It's because the brain has a close connection through the gut-brain axis.

Is your dog having digestive trouble?

Is your dog having digestive trouble?

Let our experts help!

Let our experts help!

How Do Vets Diagnose Leaky Gut in Dogs?

Our vets will begin by asking about your dog’s symptoms, diet, and environment. We'll also look for the common signs to get a good grasp of the problem. Next, we can proceed to some laboratory tests

Laboratory Tests

Different types of blood tests can show nutrient imbalances, indicated by low levels of vitamin B12. Plus, these tests can check for zonulin levels, which are proteins that increase when the gut becomes more permeable. 

Another factor we can look into is the presence of antibodies. If the level of antibodies is high, there might be an autoimmune response because of the damaged gut barrier. 

Stool tests will be used to detect parasites, infections, or signs of inflammation. 

Diagnostic Imaging

We can also use X-rays and ultrasounds to visualize the intestines and other nearby organs. If there are any blockages or abnormalities, these could give clues about what the problem is. 

Biopsy

We can also do a biopsy, a major player in diagnosing leaky gut in dogs. Our vets collect the samples from the intestine through an endoscopy, then we'll examine them under the microscope. 

Combining this with the clinical signs we observed and elevated fecal alpha-1-protease inhibitor levels, we can confirm leaky gut in the dog. 

Leaky Gut Treatment for Dogs

A veterinarian is trying to keep a dog comfortable while giving a checkup for leaky gut.

The first step to treating this condition is stabilization. This may include fluids, anti-nausea medication, or special prescription diets to calm the gut. If your dog is taking medication, then it’s important to stop these to continue with the treatment process.

Next, we’ll focus on the long-term changes, diet. We can recommend the novel or hydrolyzed protein diets for your dog so they can eat without getting sensitivities. These help reduce the inflammation while also supplying them with the nutrients they need. 

Plus, we can recommend a few whole food options such as salmon, pumpkin, and apples. These contain the necessary vitamins, minerals, and healthy fats dogs need for recovery and nutrition. 

In many cases, supplements and probiotics for dogs will be prescribed. These options provide a lot of nutritional benefits that diets alone can’t give fully. This includes omega-3 fatty acids, antioxidants, digestive enzymes, and healthy gut bacteria. 

Sometimes, we’ll need to prescribe a few pet medications for your dog’s specific condition. If the problem is caused by parasites or infections, then we might need to use antibiotics and deworming medication. 

All in all, the treatment process will be long, as leaky gut syndrome in dogs is not fixed overnight. You’ll need to stay on top of your dog’s diet, supplements, probiotics, and medication. 

Safe Home Remedies for Leaky Gut in Dogs

Leaky gut syndrome in dogs should be treated with veterinary care. These home remedies are complementary treatment options to help your dog recover at home. Try these out:

  • Homemade Bone Broth. Bone broth is packed with collagen and gelatin that help repair the intestinal lining. There are lots of options, including chicken, beef, and lamb. Just avoid adding any seasonings.

  • Fresh Pumpkin. Pumpkin is a gentle source of fiber that can help improve your dog’s digestion and stool. Add a spoonful of plain, cooked pumpkin to your dog’s meals daily. 

  • Plain Probiotic Foods. Plain, unsweetened kefir and yogurt are good, natural probiotics. These contain healthy bacteria that can help restore a healthy gut microbiome.

Can You Prevent Leaky Gut in Dogs?

Prevention is always better than a cure. While it’s not fully preventable, there are ways to reduce the risk. 

  1. Feed a High-Quality Diet

High-quality diets go a long way. Avoid cheap food with lots of fillers that can irritate the gut. Keep your dog on a consistent diet that’s equally good for its gut health. 

  1. Keep Up With Parasite Prevention

Plan your dog's checkups and treatments with us. Throughout our sessions, we can conduct stool checks and provide parasite preventives to keep track of your dog’s intestinal health. 

  1. Lower Stress Levels

Provide a happy and stable routine with plenty of exercise and enrichment for your pup. Dogs that are calm and active tend to have healthier guts and stronger immune systems. 

“Protecting our dog starts with keeping what’s inside safe and healthy.”

- Dr. Rokas Proscevicius

Final Thoughts

A leaky gut in dogs can be a problem, especially since it does a lot more than bring digestive problems. However, by starting with a consistent, high-quality diet and regular checkups, you can protect your dog and its smile.

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